India, Japan, and the United States have bilateral civilian nuclear cooperation with each other and this research paper offers a trilateral civilian nuclear cooperation strategy for the fast reactor nuclear programme among these three countries. Recently, Japan has decided to collaborate with the United States in fast reactor research and development programme. Following the India-Japan civilian nuclear cooperation and India’s successful and advanced fast reactor programme, authors propose a trilateral strategic framework to utilize bilateral to trilateral strength in the area of fast reactor programme. India’s fast reactor programme is an integral part of India’s 3 stage nuclear power programme and it is placed in the stage 2. In this direction, India has achieved significant progress and India’s Prototype Fast Breeder Reactor (PFBR) is expected to begin operation in October 2022. Fast reactors offer effective use of nuclear fuel materials in the nuclear power generation and this characteristic makes fast reactor technology more resourceful than conventional nuclear energy systems. Thus, international cooperation in fast reactor research and development can bring enhanced sustainable clean energy solutions towards net-zero carbon emissions worldwide.